Evaluation of urine examination in Childhood Nephrotic Syndrome

Document Type : Original Article

Authors

1 Biochemistry division, Chemistry department, Faculty of Science, Mansoura University

2 Children`s Hospital, Faculty of Medicine- Mansoura University

3 Pediatrics department, Faculty of Medicine, Mansoura University)

4 Biochemistry division, Chemistry department, Faculty of Science, Mansoura University.

Abstract

Pediatric Nephrotic syndrome, which is a condition affecting the kidneys, is more prevalent in children than in adults.
Aims and Objectives: To investigate urine derangement in children aged 2-12 years with nephrotic syndrome.
Patients and methods: The current study was a prospective observational pilot study on children with NS from "The Nephrology Unit of Mansoura University Children's Hospital (MUCH)." over the years 2022 & 2023. The study included Nephrotic syndrome (NS) patients who suggested glucocorticosteroid conduct as a first-line therapy. Urine examination was measured, to understand the relation between uremia and comprised renal function and develop the life quality for children grappling with CKD.
Conclusions: Uremic toxins, including urea and creatinine, accumulate in the blood as kidney function declines. These toxins can have systemic effects and contribute to the progression of CKD

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